Publications

GTP activator and dNTP substrates of HIV-1 restriction factor SAMHD1 generate a long-lived activated state

Uracil DNA glycosylase initiates degradation of HIV-1 cDNA containing misincorporated dUTP and prevents
viral integration

SAMHD1 is a single-stranded nucleic acid binding protein with no active site-associated nuclease activity

Diverse fates of uracilated HIV-1
DNA during infection of myeloid lineage cells

Seamon KJ, Sun Z, Shlyakhtenko LS, Lyubchenko YL, Stivers JT.

Nucleic Acids Res. 2015, 43, 6486-99.
Hansen, E.C. et al

eLIFE 2016,  5, e18447.
Hansen, EC, Seamon KJ,Cravens, SC,  Stivers JT.​

Proc Natl Acad Sci  2014, 111, E1843-5.    .
Weil AF, Ghosh D, Zhou Y, Seiple L, McMahon MA, Spivak AM, Siliciano RF, Stivers JT
   
Proc Natl Acad Sci  2013, 110 E448-E457.